執(zhí)照.jpg)
茶堿
分析標(biāo)準(zhǔn)品,HPLC≥98%
Theophylline
CAS號：58-55-9
分子式：C7H8N4O2
分子量：180.16
MDL：MFCD00079619
別名：1,3-二甲基黃嘌呤;2,6-二氧-1,3-二甲基嘌呤;3,7-二氫-1,3-二甲基-1H-嘌呤-2,6-二酮;2,6-二羥基-1,3-二甲基嘌呤
貨號 | 規(guī)格/參數(shù)/品牌 | 價格 | 貨期 |
YJ-B20144-50mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥200.00 | 現(xiàn)貨 |
JT91825-1ml買5贈1 | 10mM in DMSO | ￥617.00 | 現(xiàn)貨 |
產(chǎn)品介紹
Theophylline (1,3-Dimethylxanthine) 是有效的磷酸二酯酶 (PDE) 抑制劑，腺苷受體拮抗劑，和組蛋白脫乙酰酶 (HDAC) 活化劑。Theophylline (1,3-Dimethylxanthine) 抑制 PDE3 活性，放松氣道平滑肌。Theophylline (1,3-Dimethylxanthine) 通過增加 IL-10 和抑制 NF-κ B進入細(xì)胞核而具有抗炎活性。Theophylline (1,3-Dimethylxanthine) 誘發(fā)細(xì)胞凋亡 (apoptosis)。Theophylline (1,3-Dimethylxanthine) 可用于哮喘和慢性阻塞性肺疾病 (COPD) 的研究。
熔點：271-273℃
沸點：454.1℃ at 760 mmHg
外觀：白色至灰白色結(jié)晶粉末
溶解性：DMSO : 11.11 mg/mL (61.67 mM; Need ultrasonic)
H2O : 5 mg/mL (27.75 mM; Need ultrasonic)。
敏感性：對空氣敏感
儲存條件：2-8℃
注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。
參考文獻(31篇)
31. [IF=6.8] Xiao-Meng Liu et al."Precision-Oriented Theophylline-Platinum(IV) Prodrugs: Eliciting Synthetic Lethality in BRCA1-Deficient Ovarian Cancer with Enhanced Efficacy and Reduced Toxicity In Vitro and In Vivo."JOURNAL OF MEDICINAL CHEMISTRY.2025;XXXX(XXX):XXX
30. [IF=9.3] Xinxin Jia et al."The horizontally transferred gene, CsMTAN, rewired purine traffic to build caffeine factories in tea leaves."Journal of Integrative Plant Biology.2025 Jul;:
29. [IF=4.8] Zhu Yanyu et al."Multi-omics analysis of the mechanisms of abundant theacrine and EGCG3."BMC PLANT BIOLOGY.2025 Dec;25(1):1-16
28. [IF=8.5] Xinyu Feng et al."Liubao insect tea polyphenols ameliorate DSS-induced experimental colitis by protecting intestinal barrier and regulating intestinal microbiota."FOOD CHEMISTRY.2024 Nov;:142156
27. [IF=4.7] Jiayi Xu et al."Characteristic Changes and Potential Markers of Flavour in Raw Pu-Erh Tea with Different Ageing Cycles Analysed by HPLC, HS-SPME-GC-MS, and OAV."Foods.2025 Feb;14(5):829
26. [IF=7] Zixi Yang et al."Investigation of the classification criteria and flavor compounds in diversified commercially ripened Pu-erh teas."FOOD RESEARCH INTERNATIONAL.2025 Mar;:116198
25. [IF=6.5] Zixi Yang et al."Unraveling the flavor formation process of mellow and thick-type ripened Pu-erh tea through non-targeted metabolomics and metagenomics."Food Chemistry-X.2025 Mar;:102424
24. [IF=6.1] Cao Bochun et al."Innovative biomarkers TCN2 and LY6E can significantly inhibit respiratory syncytial virus infection."Journal of Translational Medicine.2024 Dec;22(1):1-18
23. [IF=8.8] Zixuan Xie et al."Mechanism of aroma enhancement methods in accelerating Congou black tea acidification subjected to room temperature storage."FOOD CHEMISTRY.2023 Nov;:137837
22. [IF=8.1] Qiuwen Yu et al."Chemometrics-based investigation of non-volatiles/volatiles flavor of tencha (Camellia sinensis cv. Yabukita, Longjing 43 and Baiye 1)."FOOD RESEARCH INTERNATIONAL.10.1016/j.foodres.2023.113461
21. [IF=5.2] Zhuanrong Wu et al."Effects of Sun Withering Degree on Black Tea Quality Revealed via Non-Targeted Metabolomics."Foods.2023 Jan;12(12):2430
20. [IF=4.342] Wei Ran et al."Comprehensive analysis of environmental factors on the quality of tea (Camellia sinensis var. sinensis) fresh leaves."SCIENTIA HORTICULTURAE.2023 Sep;319:112177
19. [IF=6.443] Yuchuan Li et al."Study on taste quality formation and leaf conducting tissue changes in six types of tea during their manufacturing processes."Food Chemistry-X.2023 Jun;18:100731
18. [IF=7.425] Shuxian Shao et al."Production regions discrimination of Huangguanyin oolong tea by using the content of chemical components and rare earth elements."FOOD RESEARCH INTERNATIONAL.2023 Mar;165:112522
17. [IF=5.318] Su Zhou et al."Pu'er raw tea extract alleviates lipid deposition in both LO2 cells and Caenorhabditis elegans."Food Bioscience.2022 Dec;50:102172
16. [IF=7.425] Jie Zhou et al."Widely targeted metabolomics using UPLC-QTRAP-MS/MS reveals chemical changes during the processing of black tea from the cultivar Camellia sinensis (L.) O. Kuntze cv. Huangjinya."FOOD RESEARCH INTERNATIONAL.2022 Dec;162:112169
15. [IF=4.072] Meng-zhen Zhou et al."Discovery and Biochemical Characterization of N-methyltransferase Genes Involved in Purine Alkaloid Biosynthetic Pathway of Camellia gymnogyna Hung T.Chang (Theaceae) from Dayao Mountain."Phytochemistry. 2022 Jul;199:113167
14. [IF=3.935] Hui Jiang et al."Preparation of covalently bonded liposome capillary column and its application in evaluation of drug membrane permeability."J Pharmaceut Biomed. 2022 Feb;209:114513
13. [IF=3.981] Lin Wang et al."Drug-drug cocrystals of theophylline with quercetin."J Drug Deliv Sci Tec. 2022 Apr;70:103228
12. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950
11. [IF=3.503] Jiajia Dong et al."Comparative pharmacokinetic analysis of raw and steamed Panax notoginseng roots in rats by UPLC-MS/MS for simultaneously quantifying seven saponins."Pharm Biol. 2021;59(1):653-661
10. [IF=3.535] Hui Jiang et al."Determination of lipid–water partition coefficient of neutral and ionic drugs by liposome electrokinetic chromatography."Electrophoresis. 2021 Aug;42(14-15):1436-1449
9. [IF=4.098] Chunlin Li et al."Discrimination of white teas produced from fresh leaves with different maturity by near-infrared spectroscopy."Spectrochim Acta A. 2020 Feb;227:117697
8. [IF=4.142] Zhang Hao et al."A portable personal glucose meter method for enzyme activity detection and inhibitory activity evaluation based on alkaline phosphatase-mediated reaction."Anal Bioanal Chem. 2021 Apr;413(9):2457-2466
7. [IF=4.411] Tao Tian et al."Personal Glucose Meter for α-Glucosidase Inhibitor Screening Based on the Hydrolysis of Maltose."Molecules. 2021 Jan;26(15):4638
6. [IF=3.894] Lixia Liu et al."Protective effects of tea polyphenols on exhaustive exercise-induced fatigue, inflammation and tissue damage."Food Nutr Res. 2017;61(1):1333390
5. [IF=3.935] Yi Tao et al."Towards the identification of alkaline phosphatase binding ligands in Li-Dan-Hua-Shi pills: A Box-Behnken design optimized affinity selection approach tandem with UHPLC-Q-TOF/MS analysis."J Pharmaceut Biomed. 2018 May;154:486
4. [IF=4.098] Chunlin Li et al."Rapid and non-destructive discrimination of special-grade flat green tea using Near-infrared spectroscopy."Spectrochim Acta A. 2019 Jan;206:254
3. [IF=4.464] Yu Jun Yang et al."The electropolymerization of CTAB on glassy carbon electrode for simultaneous determination of dopamine, uric acid, tryptophan and theophylline."J Electroanal Chem. 2016 May;768:102
2. 李承浩,王萌,任曉亮.磺化杯6芳烴對4類中藥單體成分增溶作用及其機制研究[J].中國現(xiàn)代中藥,2020,22(12):2032-2038.
1. 董燕茹,曹妍彥,盧佳純,梅思凡,河潤,陳萍.兒茶素與咖啡堿絡(luò)合物的晶體學(xué)研究[J].茶葉科學(xué),2021,41(01):80-89.
從2011年開始我們致力于在生命科學(xué)領(lǐng)域、生物醫(yī)學(xué)實驗技術(shù)及論文潤色服務(wù)，協(xié)助客戶各類實驗服務(wù)及論文潤色十余年，是客戶您值得信賴的科研合作伙伴!
如果您受時間、試驗條件等限制而無法完成您的課題研究，歡迎您與我們聯(lián)系。
實驗技術(shù)服務(wù)：
